Science is an intellectual activity to investigate the natural world and its phenomena. Although science and religion are sometimes in conflict, Buddhism is found to be unusually science-friendly. Buddhism is not only known as a religion but a philosophy and a way of life. Many famous scientists and philosophers including Albert Einstein, Charles Darwin, and Bertrand Russell, also suggested that many elements of Buddhism are considered scientific and are not outside the domain of science. This course aims to introduce the scientific approach to knowledge generation and the basic teaching of Buddha. The students will then be guided into critical analysis of the conflict and compatibility between science and Buddhism in different aspects. Importantly, students will learn to apply scientific and Buddhist philosophies to daily life and modern issues.